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Year : 2012  |  Volume : 2  |  Issue : 4  |  Page : 135-136

Hoffman's syndrome

Department of Medicine, Osmania Medical College, Osmania General Hospital, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Dr. Ravala Siddeswari
Department of Medicine, Osmania Medical College, Osmania General Hospital, Hyderabad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2249-4855.141135

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Hoffman's syndrome is characterized by hypothyroidism with muscle stiffness and pseudo hypertrophy We herewith present a case report of 28 years male with cramps of both lower limbs associated swelling of both calf muscles. Investigations revealed hypothyroidism with elevated TSH and TPO antibodies with focal hypertrophy and hyperplasia of calf muscles on biopsy with normal nerve conduction studies.

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